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​HPLC-ECD System

700 Series

> Maximum flexibility                       > Dual electrode

> Multiple pumps and detectors     > Pulse-free pump

Expandability is the keyword for the 700 Series.

Extra pumps and detectors can be added as necessary.

The standard configuration includes the ECD-700 detector equipped with one amperometric cell, the EP-700 pump unit with one microflow pump installed, and the ATC-700 temperature control unit, The pump unit also has a two channel solvent degasser built in.

HPLC-ECD-Electrochemical-Detector-700-Se

ECD-700 Electrochemical Detector

> Add an ECD to any HPLC system

> Two cells per detector possible

> Amperometric or coulometric cells

> Dual electrode

ECD700_seeinside.jpg300x300.jpg

Eicom's ECD-700 electrochemical detector offers superior stability and sensitivity.It relies on the same proven detector cell that's in the HTEC-510. Refer to the previous page for more information. When the standard amperometric cell is fitted with the optional dual electrode, the ECD-700 can monitor two voltages at the same time. A second amperometric and coulometric cell can be added to the unit at any time.

Standard Features

  • Superior sensitivity and stability of Eicom’s electrochemical detector technology.

  • Easy to maintain.

  • Maximized up-time.

  • One amperometric electrochemical detector cell with a constant voltage configuration using the same type of flow cell as the HTEC-510.

  • Available materials of working electrode; graphite, pure graphite, glassy carbon, platinum, gold, silver.

  • Easy access to the working electrode.

> ECD-700 SPECIFICATIONS

ECD-700 spec-min.jpg

EP-700 Pump Unit With Pulse-Free Mode

> Pulse quenching by computer control

> No pulse damper necessary

> Two channel degasser included

> Gradient control built in

Revolutionary pump design effectively quenches flow pulses. Cumbersome pulse damper units are no longer a necessity.

The adaptive algorithm minimizes pressure fluctuations by continually adjusting the piston velocity. Each EP-700 unit holds up to

two pumps, and there are two types to choose from, high flow or micro flow. The standard EP-700 unit comes with one microflow

pump installed.

NO More Pulse Dampers Means

> smaller volume between column and pump

> repid pressure response after starting the pump

> more accurate gradients

> EP-700 SPECIFICATIONS

EP-700spec-min.jpg

ATC-700 Temperature Controller

Temperature control provides the most stable retention times and detector signals.The ATC-700 performs this function even at room temperature due to its ability to both heat and cool.

> ATC-700 SPECIFICATIONS

ATC spec-min.jpg

​journal article

2021
・Oral acetaminophen-induced spinal 5-hydroxytriyptamine release produces analgesic effects in the rat formalin test

・l-Menthol increases extracellular dopamine and c-Fos-like immunoreactivity in the dorsal striatum, and promotes ambulatory activity
 in mice

・Photoperiodic light pulse induces ovarian development in the catfish, Mystus cavasius: Possible roles of dopamine and melatonin
 in the brain

・Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities
・5-HT2B Receptors-triggered Serotonin Release from Guinea-pig Isolated Colonic Mucosa:a Role of Endogenous Peptide YY

・Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity
・Repeated oral administration of flavan-3-ols induces browning in mice adipose tissues through sympathetic nerve activation
・Administration of cyclophosphamide to rats induces pica and potentiates 5-hydroxytryptamine synthesis in the intestine without
  causing severe intestinal injury

・The Effects of Maternal Interleukin-17A on Social Behavior, Cognitive Function, and Depression-Like Behavior in Mice with
 Altered Kynurenine Metabolites

・Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Can Extensively Differentiate to Tyrosine-Hydroxylase-Expressing
 Dopamine-Secreting Neurons

・Tyrosine hydroxylase conditional knockout mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways
・Bumble bee queens activate dopamine production and gene expression in nutritional signaling pathways in the brain
2020
・Dopamine production in the brain is associated with caste-specific morphology and behavior in an artificial intermediate honey bee caste
・Mirtazapine exerts astrocyte-mediated dopaminergic neuroprotection
・Maternal dietary imbalance between omega-6 and omega-3 fatty acids triggers the offspring’s overeating in mice
・Interaction between Mesocortical and Mesothalamic Catecholaminergic Transmissions Associated with NMDA Receptor in the
  Locus Coeruleus


・Thioredoxin as a novel sensitive marker of biological stress response in smoking


・Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice

・The Role of Serotonin in the Influence of Intense Locomotion on the Behavior Under Uncertainty in the Mollusk
 Lymnaea stagnalis


・Blockade of the renin-angiotensin system suppresses hydroxyl radical production in the rat striatum during carbon
  monoxide poisoning


・Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive  disorderShati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic
 neuronal dysfunction in the dentate gyrus Running title: Impaired neurogenesis in the Shati/Nat8l-/- mice 
2020


・Melatonin inhibits reproductive activity through changes of serotonergic activity in the brain of freshwater catfish
 (Mystus cavasius)


・Electrochemical Molecular Beacon for Nucleic Acid Sensing in a Homogeneous Solution

・An ultra-stable cytoplasmic antibody engineered for in vivo applications

・Analysis of the source of aggressiveness in gamecocks

・Serotonergic control in initiating defensive response to unexpected tactile stimulus in the trap-jaw ant Odontomachus kuroiwae

2019
・Effect of Yokukansan and Yokukansankachimpihange on Aggressive Behavior, 5-HT Receptors and Arginine Vasopressin
 ​ Expression in Social Isolation-Reared Mice


・Serotonin uptake via plasma membrane monoamine transporter during myocardial ischemia-reperfusion in the rat heart in vivo

・Selegiline Recovers Synaptic Plasticity in the Medial Prefrontal Cortex and Improves Corresponding Depression-Like Behavior
  in a Mouse Model of Parkinson’s Disease


・A Redox-Inactive Derivative of Tocotrienol Suppresses Tumor Growth of Mesothelioma Cells in a Xenograft Model

・Iso-a-acids, the bitter components of beer, improve hippocampus-dependent memory through vagus nerve activation

2018
・Prefrontal cortex miR-874-3p prevents lipopolysaccharide-induced depression-like behavior through inhibition of
 indoleamine 2,3-dioxygenase 1 expression in mice.

 

・Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in
 brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice


・Caste-specific development of the dopaminergic system during metamorphosis in female honey bees

・Functional mechanism of ASP5736, a selective serotonin 5-HT5A receptor antagonist with potential utility for the treatment
  of cognitive dysfunction in schizophrenia


2017
・Individual differences are consistent across changes in mating status and mediated by biogenic amines

・Chronopharmacological Analysis of Antidepressant Activity of a Dual-Action Serotonin Noradrenaline Reuptake Inhibitor
  (SNRI),Milnacipran, in Rats


2016
・Differential Patterning of Genes Involved in Serotonin Metabolism and Transport in Extra-embryonic Tissues of the Mouse

2015
・Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of
 diet-derived α-tocopherol


・A study on Dowager Cixi’s Yanling-Yishou-Dan of Qing Dynasty in a Japanese laboratory of biochemistry and molecular
  biology in 1990s: An attempt for TCM modernization¤

 

・Monitoring Of Blood L-DOPA And L-DOPA Metabolite Concentrations And Adverse Events In Patients With Advanced
  Parkinson’s Disease Receiving L-DOPA And Amantadine Combination Therapy: A Clinical Study


・Glutamate Input in the Dorsal Raphe Nucleus As a Determinant of Escalated Aggression in Male Mice

・Placental Tryptophan Metabolism: A Novel Pathway for the Developmental Origins of Neurological Disorders

2014
・Enhancement of Energy Expenditure following a Single Oral Dose of Flavan-3-Ols Associated with an Increase in
  Catecholamine Secretion


2012
・Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior

・Tyrosine hydroxylase gene expression is facilitated by alcohol followed by the degradation of the protein by ubiquitin
  proteasome system


・Role of Inter-Leukin-13 (IL 13), Natural killer (NK-CD57) cells and Non Neural Acetyl choline (NNAC) in patients
  with Fusobacterium varium colonized Ulcerative Colitis in Specialized Medical Hospital “SMH”


2009
Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation

Placental Transport and Metabolism: Implications for the Developmental Effects of Selective Serotonin Reuptake Inhibitors (SSRI) Antidepressants